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Red Hat Bugzilla – Attachment 318022 Details for
Bug 464460
Review Request: pypop - Python for Population Genomics
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sample-out.txt (output file that should be generated)
sample-out.txt (text/plain), 29.26 KB, created by
Alex Lancaster
on 2008-09-29 22:57:35 UTC
(
hide
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Description:
sample-out.txt (output file that should be generated)
Filename:
MIME Type:
Creator:
Alex Lancaster
Created:
2008-09-29 22:57:35 UTC
Size:
29.26 KB
patch
obsolete
>Results of data analysis >Performed on the 'sample.pop' file at: 2008-09-29-15-53-31 > > >Population Summary >================== > >Population Totals >_________________ >Sample Size (n): 47 >Allele Count (2n): 94 >Total loci in file: 9 [A, C, B, DRA, DRB1, DQA1, DQB1, DPA1, DPB1] >Total loci with data: 8 [A, C, B, DRB1, DQA1, DQB1, DPA1, DPB1] > > >Legend for all analyses >_______________________ > > * = significant at the 5% level > ** = significant at the 1% level > *** = significant at the 0.1% level > **** = significant at the 0.01% level >***** = significant at the 0.001% level > > >I. Single Locus Analyses >======================== > >1. Locus: A >___________ > >1.1. Allele Counts [A] >---------------------- >Untyped individuals: 2.0 >Sample Size (n): 45.0 >Allele Count (2n): 90 >Distinct alleles (k): 10 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0201 0.21111 19 | 0101 0.13333 12 >03012 0.15556 14 | 0201 0.21111 19 >0101 0.13333 12 | 0210 0.10000 9 >2501 0.12222 11 | 0218 0.10000 9 >0210 0.10000 9 | 03012 0.15556 14 >0218 0.10000 9 | 2501 0.12222 11 >3204 0.08889 8 | 3204 0.08889 8 >6901 0.04444 4 | 6814 0.03333 3 >6814 0.03333 3 | 6901 0.04444 4 >7403 0.01111 1 | 7403 0.01111 1 >Total 1.00000 90 | Total 1.00000 90 > > >1.2. HardyWeinberg [A] >---------------------- >Table of genotypes, format of each cell is: observed/expected. > > 0101 0/0.8 > 0201 2/2.5 6/2.0 > 0210 1/1.2 0/1.9 1/0.5 > 0218 4/1.2 0/1.9 0/0.9 1/0.5 >03012 0/1.9 0/3.0 4/1.4 0/1.4 3/1.1 > 2501 3/1.5 2/2.3 0/1.1 1/1.1 2/1.7 0/0.7 > 3204 1/1.1 1/1.7 1/0.8 0/0.8 1/1.2 3/1.0 0/0.4 > 6814 0/0.4 1/0.6 0/0.3 1/0.3 0/0.5 0/0.4 1/0.3 0/0.1 > 6901 1/0.5 0/0.8 1/0.4 1/0.4 1/0.6 0/0.5 0/0.4 0/0.1 0/0.1 > 7403 0/0.1 1/0.2 0/0.1 0/0.1 0/0.2 0/0.1 0/0.1 0/0.0 0/0.0 0/0.0 > 0101 0201 0210 0218 03012 2501 3204 6814 6901 7403 > [Cols: 1 to 10] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common No commmon genotypes; chi-square cannot be calculated > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 11 5.97 4.25 1 0.0393* >------------------------------------------------------------------------------ > All heterozygotes 34 39.03 0.65 1 0.4205 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0101 12 10.40 0.25 0.6198 > 0201 7 14.99 4.26 0.0391* > 0210 7 8.10 0.15 0.6991 > 0218 7 8.10 0.15 0.6991 > 03012 8 11.82 1.24 0.2663 > 2501 11 9.66 0.19 0.6653 > 3204 8 7.29 0.07 0.7922 > >------------------------------------------------------------------------------ >Common genotypes > Total 0 0.00 >------------------------------------------------------------------------------ > > >1.3. Slatkin's implementation of EW homozygosity test of neutrality [A] >----------------------------------------------------------------------- >Observed F: 0.1326, Expected F: 0.2654, Variance in F: 0.0083 >Normalized deviate of F (Fnd): -1.4603, p-value of F: 0.0029** > > >2. Locus: C >___________ > >2.1. Allele Counts [C] >---------------------- >Untyped individuals: 0.0 >Sample Size (n): 47.0 >Allele Count (2n): 94 >Distinct alleles (k): 15 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0307 0.29787 28 | 0102 0.23404 22 >0102 0.23404 22 | 02025 0.03191 3 >0605 0.14894 14 | 03021 0.02128 2 >1202 0.08511 8 | 0307 0.29787 28 >0712 0.05319 5 | 0403 0.01064 1 >1507 0.05319 5 | 0408 0.01064 1 >02025 0.03191 3 | 0501 0.01064 1 >03021 0.02128 2 | 0605 0.14894 14 >0403 0.01064 1 | 0712 0.05319 5 >0408 0.01064 1 | 0804 0.01064 1 >0501 0.01064 1 | 1202 0.08511 8 >0804 0.01064 1 | 1208 0.01064 1 >1208 0.01064 1 | 1301 0.01064 1 >1301 0.01064 1 | 1507 0.05319 5 >1801 0.01064 1 | 1801 0.01064 1 >Total 1.00000 94 | Total 1.00000 94 > > >2.2. HardyWeinberg [C] >---------------------- >Table of genotypes, format of each cell is: observed/expected. > > 0102 6/2.6 >02025 2/0.7 0/0.0 >03021 0/0.5 0/0.1 0/0.0 > 0307 3/6.6 0/0.9 0/0.6 7/4.2 > 0403 0/0.2 0/0.0 0/0.0 1/0.3 0/0.0 > 0408 0/0.2 0/0.0 0/0.0 0/0.3 0/0.0 0/0.0 > 0501 0/0.2 0/0.0 0/0.0 0/0.3 0/0.0 1/0.0 0/0.0 > 0605 1/3.3 0/0.4 1/0.3 5/4.2 0/0.1 0/0.1 0/0.1 2/1.0 > 0712 3/1.2 0/0.2 1/0.1 1/1.5 0/0.1 0/0.1 0/0.1 0/0.7 0/0.1 > 0804 0/0.2 0/0.0 0/0.0 0/0.3 0/0.0 0/0.0 0/0.0 0/0.1 0/0.1 0/0.0 > 1202 0/1.9 1/0.3 0/0.2 0/2.4 0/0.1 0/0.1 0/0.1 2/1.2 0/0.4 1/0.1 1/0.3 > 1208 0/0.2 0/0.0 0/0.0 1/0.3 0/0.0 0/0.0 0/0.0 0/0.1 0/0.1 0/0.0 0/0.1 0/0.0 > 1301 0/0.2 0/0.0 0/0.0 1/0.3 0/0.0 0/0.0 0/0.0 0/0.1 0/0.1 0/0.0 0/0.1 0/0.0 > 1507 0/1.2 0/0.2 0/0.1 2/1.5 0/0.1 0/0.1 0/0.1 1/0.7 0/0.3 0/0.1 2/0.4 0/0.1 > 1801 1/0.2 0/0.0 0/0.0 0/0.3 0/0.0 0/0.0 0/0.0 0/0.1 0/0.1 0/0.0 0/0.1 0/0.0 > 0102 02025 03021 0307 0403 0408 0501 0605 0712 0804 1202 1208 > [Cols: 1 to 12] > 1301 0/0.0 > 1507 0/0.1 0/0.1 > 1801 0/0.0 0/0.1 0/0.0 > 1301 1507 1801 > [Cols: 13 to 15] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 16 8.50 6.62 1 0.0101* >------------------------------------------------------------------------------ > All heterozygotes 31 38.50 1.46 1 0.2268 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0102 10 16.85 2.79 0.0951 > 0307 14 19.66 1.63 0.2018 > 0605 10 11.91 0.31 0.5791 > 1202 6 7.32 0.24 0.6258 > >------------------------------------------------------------------------------ >Common genotypes > 0102:0307 3 6.55 1.93 0.1651 > Total 3 6.55 >------------------------------------------------------------------------------ > > >2.3. Slatkin's implementation of EW homozygosity test of neutrality [C] >----------------------------------------------------------------------- >Observed F: 0.1809, Expected F: 0.1732, Variance in F: 0.0031 >Normalized deviate of F (Fnd): 0.1365, p-value of F: 0.6659 > > >3. Locus: B >___________ > >3.1. Allele Counts [B] >---------------------- >Untyped individuals: 0.0 >Sample Size (n): 47.0 >Allele Count (2n): 94 >Distinct alleles (k): 12 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >1401 0.29787 28 | 1301 0.19149 18 >1301 0.19149 18 | 1401 0.29787 28 >39021 0.12766 12 | 1520 0.07447 7 >4005 0.09574 9 | 18012 0.03191 3 >1520 0.07447 7 | 35091 0.02128 2 >51013 0.06383 6 | 39021 0.12766 12 >18012 0.03191 3 | 4005 0.09574 9 >5703 0.03191 3 | 51013 0.06383 6 >35091 0.02128 2 | 5703 0.03191 3 >67011 0.02128 2 | 67011 0.02128 2 >78021 0.02128 2 | 78021 0.02128 2 >8101 0.02128 2 | 8101 0.02128 2 >Total 1.00000 94 | Total 1.00000 94 > > >3.2. HardyWeinberg [B] >---------------------- >Table of genotypes, format of each cell is: observed/expected. > > 1301 6/1.7 > 1401 1/5.4 6/4.2 > 1520 3/1.3 2/2.1 0/0.3 >18012 1/0.6 0/0.9 1/0.2 0/0.0 >35091 0/0.4 0/0.6 0/0.1 0/0.1 0/0.0 >39021 0/2.3 6/3.6 0/0.9 0/0.4 1/0.3 1/0.8 > 4005 0/1.7 1/2.7 0/0.7 1/0.3 1/0.2 2/1.1 1/0.4 >51013 0/1.1 2/1.8 0/0.4 0/0.2 0/0.1 1/0.8 2/0.6 0/0.2 > 5703 0/0.6 2/0.9 1/0.2 0/0.1 0/0.1 0/0.4 0/0.3 0/0.2 0/0.0 >67011 0/0.4 0/0.6 0/0.1 0/0.1 0/0.0 0/0.3 0/0.2 1/0.1 0/0.1 0/0.0 >78021 1/0.4 1/0.6 0/0.1 0/0.1 0/0.0 0/0.3 0/0.2 0/0.1 0/0.1 0/0.0 0/0.0 > 8101 0/0.4 1/0.6 0/0.1 0/0.1 0/0.0 0/0.3 0/0.2 0/0.1 0/0.1 1/0.0 0/0.0 0/0.0 > 1301 1401 1520 18012 35091 39021 4005 51013 5703 67011 78021 8101 > [Cols: 1 to 12] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 14 7.72 5.10 1 0.0239* >------------------------------------------------------------------------------ > All heterozygotes 33 39.28 1.00 1 0.3166 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 1301 6 14.55 5.03 0.0250* > 1401 16 19.66 0.68 0.4092 > 1520 7 6.48 0.04 0.8377 > 39021 10 10.47 0.02 0.8850 > 4005 7 8.14 0.16 0.6899 > 51013 6 5.62 0.03 0.8716 > >------------------------------------------------------------------------------ >Common genotypes > 1301:1401 1 5.36 3.55 0.0596 > Total 1 5.36 >------------------------------------------------------------------------------ > > >3.3. Slatkin's implementation of EW homozygosity test of neutrality [B] >----------------------------------------------------------------------- >Observed F: 0.1643, Expected F: 0.2216, Variance in F: 0.0057 >Normalized deviate of F (Fnd): -0.7610, p-value of F: 0.2180 > > >4. Locus: DRA >_____________ > No data for this locus! > >5. Locus: DRB1 >______________ > >5.1. Allele Counts [DRB1] >------------------------- >Untyped individuals: 0.0 >Sample Size (n): 47.0 >Allele Count (2n): 94 >Distinct alleles (k): 7 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0802 0.29787 28 | 0402 0.22340 21 >0402 0.22340 21 | 0404 0.09574 9 >0407 0.11702 11 | 0407 0.11702 11 >1602 0.11702 11 | 0802 0.29787 28 >0404 0.09574 9 | 0901 0.08511 8 >0901 0.08511 8 | 1101 0.06383 6 >1101 0.06383 6 | 1602 0.11702 11 >Total 1.00000 94 | Total 1.00000 94 > > >5.2. HardyWeinberg [DRB1] >------------------------- >Table of genotypes, format of each cell is: observed/expected. > >0402 5/2.3 >0404 2/2.0 1/0.4 >0407 3/2.5 2/1.1 0/0.6 >0802 3/6.3 1/2.7 3/3.3 7/4.2 >0901 0/1.8 1/0.8 0/0.9 1/2.4 2/0.3 >1101 2/1.3 0/0.6 1/0.7 1/1.8 1/0.5 0/0.2 >1602 1/2.5 1/1.1 2/1.3 5/3.3 1/0.9 1/0.7 0/0.6 > 0402 0404 0407 0802 0901 1101 1602 > [Cols: 1 to 7] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 15 8.77 4.43 1 0.0352* >------------------------------------------------------------------------------ > All heterozygotes 32 38.23 1.02 1 0.3134 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0402 11 16.31 1.73 0.1887 > 0404 7 8.14 0.16 0.6899 > 0407 11 9.71 0.17 0.6796 > 0802 14 19.66 1.63 0.2018 > 0901 4 7.32 1.51 0.2199 > 1101 6 5.62 0.03 0.8716 > 1602 11 9.71 0.17 0.6796 > >------------------------------------------------------------------------------ >Common genotypes > 0402:0802 3 6.26 1.69 0.1931 > Total 3 6.26 >------------------------------------------------------------------------------ > > >5.3. Slatkin's implementation of EW homozygosity test of neutrality [DRB1] >-------------------------------------------------------------------------- >Observed F: 0.1865, Expected F: 0.3740, Variance in F: 0.0167 >Normalized deviate of F (Fnd): -1.4526, p-value of F: 0.0081* > > >6. Locus: DQA1 >______________ > >6.1. Allele Counts [DQA1] >------------------------- >Untyped individuals: 0.0 >Sample Size (n): 47.0 >Allele Count (2n): 94 >Distinct alleles (k): 5 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0201 0.32979 31 | 0201 0.32979 31 >0401 0.22340 21 | 03011 0.12766 12 >05012 0.21277 20 | 0401 0.22340 21 >03011 0.12766 12 | 0501 0.10638 10 >0501 0.10638 10 | 05012 0.21277 20 >Total 1.00000 94 | Total 1.00000 94 > > >6.2. HardyWeinberg [DQA1] >------------------------- >Table of genotypes, format of each cell is: observed/expected. > > 0201 8/5.1 >03011 4/4.0 1/0.8 > 0401 3/6.9 1/2.7 6/2.3 > 0501 4/3.3 2/1.3 1/2.2 0/0.5 >05012 4/6.6 3/2.6 4/4.5 3/2.1 3/2.1 > 0201 03011 0401 0501 05012 > [Cols: 1 to 5] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 18 10.88 4.65 1 0.0310* >------------------------------------------------------------------------------ > All heterozygotes 29 36.12 1.40 1 0.2363 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0201 15 20.78 1.61 0.2050 > 03011 10 10.47 0.02 0.8850 > 0401 9 16.31 3.28 0.0703 > 0501 10 8.94 0.13 0.7219 > 05012 14 15.74 0.19 0.6602 > >------------------------------------------------------------------------------ >Common genotypes > 0201:0201 8 5.11 1.63 0.2014 > 0201:0401 3 6.93 2.23 0.1358 > 0201:05012 4 6.60 1.02 0.3122 > Total 15 18.63 >------------------------------------------------------------------------------ > > >6.3. Slatkin's implementation of EW homozygosity test of neutrality [DQA1] >-------------------------------------------------------------------------- >Observed F: 0.2316, Expected F: 0.4865, Variance in F: 0.0249 >Normalized deviate of F (Fnd): -1.6149, p-value of F: 0.0036** > > >7. Locus: DQB1 >______________ > >7.1. Allele Counts [DQB1] >------------------------- >Untyped individuals: 0.0 >Sample Size (n): 47.0 >Allele Count (2n): 94 >Distinct alleles (k): 6 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >03032 0.29787 28 | 0202 0.21277 20 >06011 0.22340 21 | 0301 0.11702 11 >0202 0.21277 20 | 03032 0.29787 28 >0301 0.11702 11 | 0304 0.08511 8 >0304 0.08511 8 | 05031 0.06383 6 >05031 0.06383 6 | 06011 0.22340 21 >Total 1.00000 94 | Total 1.00000 94 > > >7.2. HardyWeinberg [DQB1] >------------------------- >Table of genotypes, format of each cell is: observed/expected. > > 0202 3/2.1 > 0301 3/2.3 0/0.6 >03032 4/6.0 5/3.3 7/4.2 > 0304 1/1.7 1/0.9 1/2.4 2/0.3 >05031 1/1.3 1/0.7 1/1.8 1/0.5 0/0.2 >06011 5/4.5 1/2.5 3/6.3 0/1.8 2/1.3 5/2.3 > 0202 0301 03032 0304 05031 06011 > [Cols: 1 to 6] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 17 9.82 5.25 1 0.0219* >------------------------------------------------------------------------------ > All heterozygotes 30 37.18 1.39 1 0.2389 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0202 14 15.74 0.19 0.6602 > 0301 11 9.71 0.17 0.6796 > 03032 14 19.66 1.63 0.2018 > 0304 4 7.32 1.51 0.2199 > 05031 6 5.62 0.03 0.8716 > 06011 11 16.31 1.73 0.1887 > >------------------------------------------------------------------------------ >Common genotypes > 0202:03032 4 5.96 0.64 0.4226 > 03032:06011 3 6.26 1.69 0.1931 > Total 7 12.21 >------------------------------------------------------------------------------ > > >7.3. Slatkin's implementation of EW homozygosity test of neutrality [DQB1] >-------------------------------------------------------------------------- >Observed F: 0.2089, Expected F: 0.4232, Variance in F: 0.0199 >Normalized deviate of F (Fnd): -1.5173, p-value of F: 0.0053* > > >8. Locus: DPA1 >______________ > >8.1. Allele Counts [DPA1] >------------------------- >Untyped individuals: 1.0 >Sample Size (n): 46.0 >Allele Count (2n): 92 >Distinct alleles (k): 3 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0103 0.59783 55 | 0103 0.59783 55 >02011 0.22826 21 | 02011 0.22826 21 >02013 0.17391 16 | 02013 0.17391 16 >Total 1.00000 92 | Total 1.00000 92 > > >8.2. HardyWeinberg [DPA1] >------------------------- >Table of genotypes, format of each cell is: observed/expected. > > 0103 17/16.4 >02011 11/12.6 2/2.4 >02013 10/9.6 6/3.7 0/1.4 > 0103 02011 02013 > [Cols: 1 to 3] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common N/A N/A 0.23 1 0.6306 >------------------------------------------------------------------------------ > Lumped genotypes N/A N/A 0.04 1 0.8374 >------------------------------------------------------------------------------ > Common + lumped N/A N/A 0.27 1 0.6011 >------------------------------------------------------------------------------ > All homozygotes 19 20.23 0.07 1 0.7848 >------------------------------------------------------------------------------ > All heterozygotes 27 25.77 0.06 1 0.8088 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0103 21 22.12 0.06 0.8118 > 02011 17 16.21 0.04 0.8437 > 02013 16 13.22 0.59 0.4440 > >------------------------------------------------------------------------------ >Common genotypes > 0103:0103 17 16.44 0.02 0.8902 > 0103:02011 11 12.55 0.19 0.6609 > 0103:02013 10 9.57 0.02 0.8882 > Total 38 38.56 >------------------------------------------------------------------------------ > > >8.3. Slatkin's implementation of EW homozygosity test of neutrality [DPA1] >-------------------------------------------------------------------------- >Observed F: 0.4397, Expected F: 0.6683, Variance in F: 0.0326 >Normalized deviate of F (Fnd): -1.2664, p-value of F: 0.0993 > > >9. Locus: DPB1 >______________ > >9.1. Allele Counts [DPB1] >------------------------- >Untyped individuals: 3.0 >Sample Size (n): 44.0 >Allele Count (2n): 88 >Distinct alleles (k): 7 > >Counts ordered by frequency | Counts ordered by name >Name Frequency (Count) | Name Frequency (Count) >0403 0.37500 33 | 0202 0.02273 2 >1401 0.32955 29 | 0403 0.37500 33 >5801 0.13636 12 | 1401 0.32955 29 >3901 0.06818 6 | 1901 0.03409 3 >1901 0.03409 3 | 3901 0.06818 6 >4901 0.03409 3 | 4901 0.03409 3 >0202 0.02273 2 | 5801 0.13636 12 >Total 1.00000 88 | Total 1.00000 88 > > >9.2. HardyWeinberg [DPB1] >------------------------- >Table of genotypes, format of each cell is: observed/expected. > >0202 0/0.0 >0403 0/0.8 5/6.2 >1401 0/0.7 12/10.9 7/4.8 >1901 1/0.1 0/1.1 0/1.0 0/0.1 >3901 1/0.1 2/2.3 1/2.0 1/0.2 0/0.2 >4901 0/0.1 1/1.1 0/1.0 1/0.1 1/0.2 0/0.1 >5801 0/0.3 8/4.5 2/4.0 0/0.4 0/0.8 0/0.4 1/0.8 > 0202 0403 1401 1901 3901 4901 5801 > [Cols: 1 to 7] > > Observed Expected Chi-square DoF p-value >------------------------------------------------------------------------------ > Common Too many parameters for chi-square test. > >------------------------------------------------------------------------------ > Lumped genotypes Value not calculated. > >------------------------------------------------------------------------------ > Common + lumped Value not calculated. > >------------------------------------------------------------------------------ > All homozygotes 13 12.11 0.06 1 0.7990 >------------------------------------------------------------------------------ > All heterozygotes 31 31.89 0.02 1 0.8753 >------------------------------------------------------------------------------ >Common heterozygotes by allele > 0403 23 20.63 0.27 0.6010 > 1401 15 19.44 1.02 0.3136 > 3901 6 5.59 0.03 0.8626 > 5801 10 10.36 0.01 0.9101 > >------------------------------------------------------------------------------ >Common genotypes > 0403:0403 5 6.19 0.23 0.6331 > 0403:1401 12 10.88 0.12 0.7330 > Total 17 17.06 >------------------------------------------------------------------------------ > > >9.3. Slatkin's implementation of EW homozygosity test of neutrality [DPB1] >-------------------------------------------------------------------------- >Observed F: 0.2753, Expected F: 0.3693, Variance in F: 0.0161 >Normalized deviate of F (Fnd): -0.7415, p-value of F: 0.2536 > > > >II. Multi-locus Analyses >======================== > >Haplotype / linkage disequilibrium (LD) statistics >__________________________________________________ > >Pairwise LD estimates >--------------------- >Locus pair D D' Wn ln(L_1) ln(L_0) S # permu p-value >A:C 0.01465 0.49229 0.39472 -289.09 -326.81 75.44 - - >A:B 0.01503 0.51142 0.40001 -293.47 -330.84 74.73 - - >A:DRB1 0.01395 0.44396 0.37769 -282.00 -309.16 54.32 - - >A:DQA1 0.01219 0.33413 0.36466 -269.57 -286.08 33.02 - - >A:DQB1 0.01356 0.39266 0.37495 -275.58 -297.62 44.07 - - >A:DPA1 0.01682 0.32399 0.36667 -219.78 -226.97 14.38 - - >A:DPB1 0.01362 0.42240 0.40404 -237.85 -262.06 48.42 - - >C:B 0.04135 0.89434 0.84992 -210.37 -342.68 264.63 - - >C:DRB1 0.01698 0.48046 0.47513 -280.34 -317.66 74.62 - - >C:DQA1 0.02072 0.47797 0.49368 -263.23 -293.74 61.01 - - >C:DQB1 0.01766 0.45793 0.49879 -269.55 -305.28 71.46 - - >C:DPA1 0.02039 0.41030 0.46438 -224.72 -236.52 23.61 - - >C:DPB1 0.01898 0.46442 0.36990 -242.45 -268.46 52.01 - - >B:DRB1 0.01745 0.50109 0.41670 -286.79 -320.50 67.42 - - >B:DQA1 0.01847 0.44283 0.43422 -271.36 -296.59 50.45 - - >B:DQB1 0.01958 0.49040 0.43654 -277.30 -308.13 61.65 - - >B:DPA1 0.01875 0.37438 0.40118 -229.76 -239.16 18.80 - - >B:DPB1 0.01898 0.46082 0.38001 -247.84 -272.77 49.86 - - >DRB1:DQA1 0.06145 0.92556 0.91975 -164.06 -271.56 214.99 - - >DRB1:DQB1 0.06058 1.00000 1.00000 -147.74 -283.10 270.72 - - >DRB1:DPA1 0.02795 0.38642 0.39936 -202.51 -211.42 17.81 - - >DRB1:DPB1 0.01291 0.32216 0.32030 -231.03 -247.29 32.53 - - >DQA1:DQB1 0.06876 0.92556 0.92384 -152.52 -259.18 213.33 - - >DQA1:DPA1 0.02242 0.25405 0.27212 -185.25 -189.23 7.97 - - >DQA1:DPB1 0.01617 0.30441 0.34388 -210.93 -226.09 30.33 - - >DQB1:DPA1 0.02740 0.34112 0.36604 -193.17 -200.77 15.20 - - >DQB1:DPB1 0.01145 0.26607 0.30921 -222.73 -236.89 28.34 - - >DPA1:DPB1 0.02008 0.28507 0.35928 -165.96 -173.31 14.68 - - > > >
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