After evaluating this issue, there are no plans to address it further or fix it in an upcoming release. Therefore, it is being closed. If plans change such that this issue will be fixed in an upcoming release, then the bug can be reopened.
CentOS stream MR with relevant change: https://gitlab.com/redhat/centos-stream/rpms/nodejs/-/merge_requests/57
There are still issues present on the s390x architecture (see attachment below). Due to the time constraints, I'm returning this to backlog.