Clamd in fedora lack of a sane default config and initscript which are expected from system services by users. Other distros including the security-craze openbsd also includes a sane default config, so I dont see a reason why we shouldn't include that too in fedora. If you need help in creating one, I'm able to volunteer.
The clamav-scanner subpackage contains a setup suitable for streambased scanning. A generic setup for a server doing directory- or filebased scanning is not possible due to file permissions.