This error might in fact be in the way that gnome-tweak-tool uses pygobject, I don't know for sure, but it's trivially reproducible from python prompt as well. What this boils down to is the following one-liner: $ python Python 2.7.2 (default, Feb 9 2012, 22:06:37) [GCC 4.6.2 20111027 (Red Hat 4.6.2-1)] on linux2 Type "help", "copyright", "credits" or "license" for more information. >>> from gi.repository import Gtk Traceback (most recent call last): File "<stdin>", line 1, in <module> File "/usr/lib64/python2.7/site-packages/gi/importer.py", line 76, in load_module dynamic_module._load() File "/usr/lib64/python2.7/site-packages/gi/module.py", line 224, in _load overrides_modules = __import__('gi.overrides', fromlist=[self._namespace]) File "/usr/lib64/python2.7/site-packages/gi/overrides/Gtk.py", line 1419, in <module> raise RuntimeError("Gtk couldn't be initialized") RuntimeError: Gtk couldn't be initialized The backtrace that I'm getting from gnome-tweak-tool looks like this: ]$ gnome-tweak-tool Traceback (most recent call last): File "/usr/bin/gnome-tweak-tool", line 75, in <module> from gtweak.mainwindow import MainWindow File "/usr/lib/python2.7/site-packages/gtweak/mainwindow.py", line 20, in <module> from gi.repository import Gtk File "/usr/lib64/python2.7/site-packages/gi/importer.py", line 76, in load_module dynamic_module._load() File "/usr/lib64/python2.7/site-packages/gi/module.py", line 224, in _load overrides_modules = __import__('gi.overrides', fromlist=[self._namespace]) File "/usr/lib64/python2.7/site-packages/gi/overrides/Gtk.py", line 1419, in <module> raise RuntimeError("Gtk couldn't be initialized") RuntimeError: Gtk couldn't be initialized Version-Release number of selected component (if applicable): $ rpm -q gnome-tweak-tool pygobject3 gnome-tweak-tool-3.2.2-2.fc16.noarch pygobject3-3.0.3-1.fc16.ppc64 How reproducible: Always Steps to Reproduce: 1. python -c 'from gi.repository import Gtk' Actual results: Stack trace Expected results: <module 'Gtk'> or some such Additional info: I'm not sure this is relevant, but note that this is happening on ppc64.
I see this error when trying to start /usr/libexec/ibus-engine-anthy in F17/x86_64 with pygobject3-3.2.2-1
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