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If you need to manually set the irq affinity, it's possible that irqbalance is not configured correctly.

Try

cat /proc/irq/{46,47,48,49}/affinity_hint

(The numbers should match those shown in /proc/interrupts for virtio-scsi).  It should show something like this:

1
2
4
8

(In reply to Paolo Bonzini from comment #18)
> If you need to manually set the irq affinity, it's possible that irqbalance
> is not configured correctly.
> 
> Try
> 
> cat /proc/irq/{46,47,48,49}/affinity_hint
> 
> (The numbers should match those shown in /proc/interrupts for virtio-scsi). 
> It should show something like this:
> 
> 1
> 2
> 4
> 8

Paolo, very sorry that it has been quite out of my mind. I will check affinity_hint number and update the fresh performance results this week.

Thanks,
Xiaomei