Adobe Reader was built to use insecure RPATH in the binary. This issue could possibly be exploited by a local attacker to run arbitrary code as some other user if victim user can be convinced to run Adobe Reader in an attacker controlled directory with specially crafted content.
Public now via upstream security bulletin: http://www.adobe.com/support/security/bulletins/apsb08-19.html
This issue was addressed in: Red Hat Enterprise Linux Extras: http://rhn.redhat.com/errata/RHSA-2008-0974.html