ran the following python test code to verify:

import unittest
from sqlalchemy import create_engine
from sqlalchemy import exc


class MysqlFailureCase(unittest.TestCase):
    def setUp(self):
        self.engine = create_engine(
            "mysql+mysqldb://xxx:xxx@localhost/test")

    def test_mysql_operror(self):
        connection = self.engine.connect()
        raw_conn = connection.connection

        # use raw commands to place the connection into
        # a state where additional queries are not allowed
        raw_conn.query("select 1")
        raw_result = raw_conn.use_result()

        # use the SQLAlchemy connection to try to execute a statement;
        # this raises ProgrammingError on MySQLdb
        # (usually raises OperationalError on others)
        self.assertRaises(
            exc.ProgrammingError,
            connection.execute, "select 1"
        )

        # the engine and connection pool is flushed totally,
        # and on subsequent use reconnects and works again
        self.assertEqual(
            connection.scalar("select 1"), 1
        )


if __name__ == '__main__':
    unittest.main()

Since the problem described in this bug report should be
resolved in a recent advisory, it has been closed with a
resolution of ERRATA.

For information on the advisory, and where to find the updated
files, follow the link below.

If the solution does not work for you, open a new bug report.

https://rhn.redhat.com/errata/RHBA-2015-0825.html