Hello,

 - Use a more meaningful name for your archive, with:

Source0:        https://github.com/twilio/twilio-python/archive/%{version}/%{name}-%{version}.tar.gz

 - I don't think this is necessary:

# sitelib for noarch packages, sitearch for others (remove the unneeded one)
%{!?__python2: %global __python2 %__python}
%{!?python2_sitelib: %global python2_sitelib %(%{__python2} -c "from distutils.sysconfig import get_python_lib; print(get_python_lib())")}

python2_sitelib is already defined in Fedora.

 - Use the appropriate python macros:

%{__python2} setup.py build ⇒ %py2_build

%{__python3} setup.py build ⇒ %py3_build

%{__python3} setup.py install -O1 --skip-build --root $RPM_BUILD_ROOT ⇒ %py3_install

%{__python2} setup.py install -O1 --skip-build --root $RPM_BUILD_ROOT ⇒ %py2_install

 - add the examples directory to %doc:

%doc README.rst examples

 - python2-twilio.noarch: E: description-line-too-long C The Twilio REST SDK simplifies the process of making calls using the Twilio REST API.

Split your description to stay under 80 characters per line.

 - python-twilio.src:26: W: mixed-use-of-spaces-and-tabs (spaces: line 14, tab: line 26)

Use either spaces or tabs, not both.

 - You could use the %{py2_dist/%{py3_dist macros to handle your Python dependencies. See https://fedoraproject.org/wiki/Packaging:Python#Requires_and_BuildRequires_with_standardized_names

BuildRequires:  python2-devel
BuildRequires:  %{py2_dist nose}
BuildRequires:  %{py2_dist pytz}
BuildRequires:  %{py2_dist six}
BuildRequires:  %{py2_dist mock}
BuildRequires:  python2-jwt
BuildRequires:  %{py2_dist requests}

%if %{with python3}
BuildRequires:  python3-devel
BuildRequires:  %{py3_dist nose}
BuildRequires:  %{py3_dist pytz}
BuildRequires:  %{py3_dist six}
BuildRequires:  %{py3_dist mock}
BuildRequires:  python3-jwt
BuildRequires:  %{py3_dist requests}
%endif # with python3

%description
%{desc}

#python2 subpackage
%package -n python2-twilio
Summary:        %{sum}

Requires:   %{py2_dist six}
Requires:   %{py2_dist requests}
Requires:   python2-jwt
Requires:   %{py2_dist pytz}

%{?python_provide:%python_provide python2-twilio}

%description -n python2-twilio
%{desc}

#python3 subpackage
%if %{with python3}
%package -n python3-twilio
Summary:        %{sum}

Requires:   %{py3_dist six}
Requires:   %{py3_dist requests}
Requires:   python3-jwt
Requires:   %{py3_dist pytz}

> python2_sitelib is already defined in Fedora.
Ah ok - I got that from the template created by newspec



Spec URL: https://mich181189.fedorapeople.org/python-twilio/python-twilio.spec
SRPM URL: https://mich181189.fedorapeople.org/python-twilio/python-twilio-6.8.0-1.fc26.src.rpm

All ok, package accepted.

(fedrepo-req-admin):  The Pagure repository was created at https://src.fedoraproject.org/rpms/python-twilio

python-twilio-6.8.0-1.fc27 has been submitted as an update to Fedora 27. https://bodhi.fedoraproject.org/updates/FEDORA-2017-98f1a0a410

python-twilio-6.8.0-1.fc27 has been pushed to the Fedora 27 testing repository. If problems still persist, please make note of it in this bug report.
See https://fedoraproject.org/wiki/QA:Updates_Testing for
instructions on how to install test updates.
You can provide feedback for this update here: https://bodhi.fedoraproject.org/updates/FEDORA-2017-98f1a0a410

python-twilio-6.8.0-1.fc26 has been submitted as an update to Fedora 26. https://bodhi.fedoraproject.org/updates/FEDORA-2017-36f9e309ec

python-twilio-6.8.0-1.fc26 has been pushed to the Fedora 26 stable repository. If problems still persist, please make note of it in this bug report.

python-twilio-6.8.0-1.fc27 has been pushed to the Fedora 27 stable repository. If problems still persist, please make note of it in this bug report.