A remote code execution vulnerability exists when Microsoft .NET Framework processes untrusted input, aka ".NET Framework Remote Code Execution Vulnerability." This affects Microsoft .NET Framework 4.6, Microsoft .NET Framework 3.5, Microsoft .NET Framework 4.7/4.7.1/4.7.2, Microsoft .NET Framework 3.0, Microsoft .NET Framework 3.5.1, Microsoft .NET Framework 4.6.2/4.7/4.7.1/4.7.2, Microsoft .NET Framework 4.5.2, Microsoft .NET Framework 4.6/4.6.1/4.6.2/4.7/4.7.1/4.7.1/4.7.2, Microsoft .NET Framework 4.7.1/4.7.2, Microsoft .NET Framework 4.7.2, Microsoft .NET Framework 2.0.

References:

https://portal.msrc.microsoft.com/en-US/security-guidance/advisory/CVE-2018-8421