It appears that sane-backends knows how to tell hotplug how to fix the permissions for the Epson Perfection 2480 Photo scanner, by creating /etc/hotplug/usb/libsane.usermap and /etc/hotplug/usb/libusbscanner, but that support for usb was recently removed from hotplug and moved to udev, and sane-backends does *not* know how to tell udev to do the right thing with this scanner or all the other ones listed in /etc/hotplug/usb/libsane.usermap. I assume that this is a bug with sane-backends rather than a bug with udev, but it seems to me that hotplug usb support shouldn't have been removed when there were packages such as sane-backends still depending on it.
sane-backends-1.0.17-5.fc5.9 contains this entry for your scanner in /etc/udev/rules.d/60-libsane.rules: # Epson Corp.|Perfection 2400 Photo SYSFS{idVendor}=="04b8", SYSFS{idProduct}=="011b", SYMLINK+="scanner-%k" Please verify whether your problem still persists.
Seems fine in current Raw hide, thanks.