I'm having a very similar problem, although my error syntax is a little
different.  This is from Fedroa 6 on x86_64:

[sleepylight@lucent ~]$ f-spot
Starting new FSpot server
XXXXX
Mono.Data.SqliteClient.SqliteSyntaxException: file is encrypted or is not a database
  at Mono.Data.SqliteClient.SqliteCommand.GetNextStatement (IntPtr pzStart,
System.IntPtr pzTail, System.IntPtr pStmt) [0x00000] 
  at Mono.Data.SqliteClient.SqliteCommand.ExecuteReader (CommandBehavior
behavior, Boolean want_results, System.Int32 rows_affected) [0x00000] 
  at Mono.Data.SqliteClient.SqliteCommand.ExecuteNonQuery () [0x00000] 
  at MetaStore.CreateTable () [0x00000] 
  at MetaStore..ctor (Mono.Data.SqliteClient.SqliteConnection connection,
Boolean is_new) [0x00000] 
  at Db.Init (System.String path, Boolean create_if_missing) [0x00000] 
  at FSpot.Core..ctor () [0x00000] 
  at FSpot.Driver.Main (System.String[] args) [0x00000] 
XXXXX
Starting new FSpot server
Starting new FSpot server
Starting new FSpot server

=================================================================
Got a SIGSEGV while executing native code. This usually indicates
a fatal error in the mono runtime or one of the native libraries 
used by your application.
=================================================================

Stacktrace:

  at (wrapper managed-to-native) System.Threading.Monitor.Monitor_try_enter
(object,int) <0x0000b>
  at (wrapper managed-to-native) System.Threading.Monitor.Monitor_try_enter
(object,int) <0xffffffff>
  at System.Threading.Monitor.Enter (object) <0x00026>
  at (wrapper synchronized) DBus.Service.remove_SignalCalled
(DBus.Service/SignalCalledHandler) <0xffffffff>
  at FSpot.Core.Proxy.Finalize () <0x0001d>
  at (wrapper runtime-invoke) System.Object.runtime_invoke_void
(object,intptr,intptr,intptr) <0xffffffff>

Native stacktrace:

        f-spot(mono_handle_native_sigsegv+0xe7) [0x517337]
        f-spot [0x4e490d]
        /lib64/libpthread.so.0 [0x3020a0dde0]
        f-spot [0x479b10]
        f-spot [0x479ee4]
        [0x4002129b]
Abort
[sleepylight@lucent ~]$ rpm -q mono-core
mono-core-1.1.17.1-4.fc6
[sleepylight@lucent ~]$ rpm -q mysql
mysql-5.0.27-1.fc6

Fedora apologizes that these issues have not been resolved yet. We're
sorry it's taken so long for your bug to be properly triaged and acted
on. We appreciate the time you took to report this issue and want to
make sure no important bugs slip through the cracks.

If you're currently running a version of Fedora Core between 1 and 6,
please note that Fedora no longer maintains these releases. We strongly
encourage you to upgrade to a current Fedora release. In order to
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for releases which are no longer maintained and closing them.
http://fedoraproject.org/wiki/LifeCycle/EOL

If this bug is still open against Fedora Core 1 through 6, thirty days
from now, it will be closed 'WONTFIX'. If you can reporduce this bug in
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Thanks for your help, and we apologize again that we haven't handled
these issues to this point.

The process we are following is outlined here:
http://fedoraproject.org/wiki/BugZappers/F9CleanUp

We will be following the process here:
http://fedoraproject.org/wiki/BugZappers/HouseKeeping to ensure this
doesn't happen again.

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This bug is open for a Fedora version that is no longer maintained and
will not be fixed by Fedora. Therefore we are closing this bug.

If you can reproduce this bug against a currently maintained version of
Fedora please feel free to reopen thus bug against that version.

Thank you for reporting this bug and we are sorry it could not be fixed.