This issue cannot be reproduced on latest rhel8.4. Following steps in Description, both ovs and qemu keep working well.
Versions:
4.18.0-278.rt7.43.el8.dt4.x86_64
qemu-kvm-5.2.0-4.module+el8.4.0+9676+589043b9.x86_64
tuned-2.15.0-1.el8.noarch
libvirt-7.0.0-3.module+el8.4.0+9709+a99efd61.x86_64
python3-libvirt-6.10.0-1.module+el8.4.0+8948+a39b3f3a.x86_64
openvswitch2.13-2.13.0-86.el8fdp.x86_64
dpdk-20.11-1.el8.x86_64
So close this bz as CurrentRelease. Feel free to let me know if any concerns. Thanks.