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It looks like the lsusb detects the reader correctly. The opensc looks like it can talk to the pcscs fine too, but the pcscd debug log does not mention the omnikey reader at all.

Grepping through the stig profile, I noticed there is usbguard configured as part of the process. Does it have some logs? Does stopping/disabling the usbguard helps?

Is it something new in the STIG profile or something that has changed in openscap? I will move it to the openscap anyway as it does not look like something that can be fixed inside of opensc.

Fixed by https://github.com/ComplianceAsCode/content/pull/7105 which is already in 0.1.57

Since the problem described in this bug report should be
resolved in a recent advisory, it has been closed with a
resolution of ERRATA.

For information on the advisory (scap-security-guide bug fix and enhancement update), and where to find the updated
files, follow the link below.

If the solution does not work for you, open a new bug report.

https://access.redhat.com/errata/RHBA-2021:4265