Please branch and build python-scikit-image in epel10. If you do not wish to maintain python-scikit-image in epel10, or do not think you will be able to do this in a timely manner, I would be happy to be a co-maintainer of the package (FAS: kkeithle); please add me through https://src.fedoraproject.org/rpms/python-scikit-image/adduser
I've added you as an EPEL collaborator.
I was able to build python-dask without this and this has many dependencies, including xorg-x11-Xvfb, and Xvfb won't be built for epel10