JupyterLab is an extensible environment for interactive and reproducible computing, based on the Jupyter Notebook Architecture. From JupyterLab 4.0.0 until 4.5.11 and 4.6.4, the PyPI Extension Manager uninstall request reaches ExtensionHandler.post, which validates extension names for installation but passes uninstall names to PyPIExtensionManager.uninstall and python -m pip uninstall without rejecting option-like values. The security impact requires that the PyPI Extension Manager is enabled, the account can call the extension API, and kernels and terminals are disabled or delegated to remote hosts; otherwise the user can already read files and make outbound requests directly. An authenticated user with extension API access can supply a pip requirements option to make the server read a local file or fetch an internal URL, and reflected parse errors can return the first unparsable line or response content. A pip log option can also create or corrupt a chosen path with pip-generated log text, but the requester cannot select an arbitrary disclosed line or arbitrary file content, and the injection does not add code execution or availability impact beyond ordinary package removal. This issue is fixed in JupyterLab 4.5.11 and 4.6.4.