Description of problem: Mod_wsgi in Fedora EPEL is built with static python. This has two problems. A) Consumes extra memory B) Is incompatible with other python-related modules in apache, such as mod_python. How reproducible: Always. Steps to Reproduce: Known issue, read the link Additional info: Known issue. Read about it at http://code.google.com/p/modwsgi/wiki/InstallationIssues. Sections "Lack Of Python Shared Library" and "Using ModPython and ModWsgi" are particularly interesting. I've tested the proposed solutions against mod_wsgi 2.0, and that seems to work.
This is fixed in 1.3-3.el5, currently in testing.