I'm assuming this is an initscripts, but don't know that for certain... With current updates from rawhide, sound settings aren't preserved across reboot. Every time I reboot, my speakers are muted and the main volume is set all the way down to 0. Anything I can tell you to help track this down, please let me know...
Seems like something simple we should fix prior to GA that is a regression from prior releases. Adding to F10blocker.
*** This bug has been marked as a duplicate of bug 462337 ***