Description of problem:
Running F10 beta x86_64, I installed the latest Flash player from Adobe (flash-plugin-10.0.12.36-release.i386).  SELinux blocked me from hearing any sound.  audit2why gave me:

[root@case ~]# audit2why -i /var/log/audit/audit.log 
type=AVC msg=audit(1224250708.604:353): avc:  denied  { read } for  pid=24270 comm="npviewer.bin" name="70bdfe81117ed4ee5e56a93d48f73bd9:runtime" dev=0:13 ino=16646214 scontext=unconfined_u:unconfined_r:nsplugin_t:s0-s0:c0.c1023 tcontext=system_u:object_r:nfs_t:s0 tclass=lnk_file

	Was caused by:
		Missing type enforcement (TE) allow rule.

		You can use audit2allow to generate a loadable module to allow this access.

audit2allow gave me:

module local 1.0;

require {
	type nsplugin_t;
	type nfs_t;
	class lnk_file read;
}

#============= nsplugin_t ==============
allow nsplugin_t nfs_t:lnk_file read;

After loading that that, I was able to hear audio.