Doesn't build on ppc64.

 gcc -DPACKAGE_NAME=\"libspatialite\" -DPACKAGE_TARNAME=\"libspatialite\" -DPACKAGE_VERSION=\"2.4.0\" "-DPACKAGE_STRING=\"libspatialite 2.4.0\"" -DPACKAGE_BUGREPORT=\"a.furieri\" -DPACKAGE=\"libspatialite\" -DVERSION=\"2.4.0\" -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STDIO_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_MATH_H=1 -DHAVE_FLOAT_H=1 -DHAVE_FCNTL_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDDEF_H=1 -DHAVE_STDINT_H=1 -DHAVE_SYS_TIME_H=1 -DHAVE_UNISTD_H=1 -DHAVE_SQLITE3_H=1 -DHAVE_SQLITE3EXT_H=1 -DHAVE_DLFCN_H=1 -DTIME_WITH_SYS_TIME=1 -DLSTAT_FOLLOWS_SLASHED_SYMLINK=1 -DLSTAT_FOLLOWS_SLASHED_SYMLINK=1 -DHAVE_STRFTIME=1 -DHAVE_MEMSET=1 -DHAVE_STRCASECMP=1 -DHAVE_STRERROR=1 -DHAVE_STRNCASECMP=1 -DHAVE_STRSTR=1 -DHAVE_FDATASYNC=1 -DHAVE_FTRUNCATE=1 -DHAVE_GETCWD=1 -DHAVE_GETTIMEOFDAY=1 -DHAVE_LOCALTIME_R=1 -DHAVE_MEMMOVE=1 -DHAVE_STRERROR=1 -DHAVE_LIBSQLITE3=1 -DHAVE_PROJ_API_H=1 -DHAVE_GEOS_C_H=1 -DHAVE_ICONV_H=1 -I. -O2 -g -pipe -Wall -Wp,-D_FORTIFY_SOURCE=2 -fexceptions -fstack-protector --param=ssp-buffer-size=4 -m64 -mminimal-toc -I../../src/headers -D_LARGE_FILE=1 -D_FILE_OFFSET_BITS=64 -D_LARGEFILE_SOURCE=1 -DNDEBUG=1 -DOMIT_GEOCALLBACKS -O2 -g -pipe -Wall -Wp,-D_FORTIFY_SOURCE=2 -fexceptions -fstack-protector --param=ssp-buffer-size=4 -m64 -mminimal-toc -MT srs_init.lo -MD -MP -MF .deps/srs_init.Tpo -c srs_init.c  -fPIC -DPIC -o .libs/srs_init.o
{standard input}: Assembler messages:
{standard input}:128092: Error: operand out of range (0x0000000000008000 is not between 0xffffffffffff8000 and 0x0000000000007ffc)
{standard input}:128111: Error: operand out of range (0x0000000000008008 is not between 0xffffffffffff8000 and 0x0000000000007ffc)
{standard input}:128123: Error: operand out of range (0x0000000000008010 is not between 0xffffffffffff8000 and 0x0000000000007ffc)
{standard input}:128170: Error: operand out of range (0x0000000000008018 is not between 0xffffffffffff8000 and 0x0000000000007ffc)

... and so on, and so on.

Informed upstream here: http://groups.google.com/group/spatialite-users/browse_thread/thread/691e7c9460d8cb81