http://kojipkgs.fedoraproject.org/packages/avogadro/1.0.3/1.fc16/data/logs/x86_64/build.log avogadro-debuginfo 1.0.3-1 is empty; -Wl,-s in the compiler flags looks like a probable cause. 1.0.1-15 did not have this problem.
Whoops (grrr, another build system regression in what's supposed to be a stable bugfix release from upstream), I'm now building a fixed avogadro-1.0.3-2.fc16 package for Rawhide. I also revoked the testing push requests for avogadro-1.0.3-1.fc1[345], I'll replace them with fixed builds. Thanks for noticing this!
avogadro-1.0.3-2.fc16 has valid debuginfo, I'm now issuing new builds for F13/F14/F15 updates-testing to replace the bad ones.