https://fedoraproject.org/wiki/Packaging:AutoProvidesAndRequiresFiltering

If using the suggested method to prevent python modules
if will stop due to something missing in %filter_setup:

$ rpm -E "'%filter_setup'"
' 
'

and suggested method is:
%{?filter_setup:
%filter_provides_in %{python_sitearch}/.*\.so$
%filter_setup
}

I noticed several packages use a pattern like:
%global __provides_exclude_from	^%{python_sitearch}/.*\\.so$
that appears to work.

I see this in rawhide and f17:
$ rpm --showrc | grep __provides_exclude_from
%global __provides_exclude_from %{perl_vendorarch}/auto/.*\\.so$|%{perl_archlib}/.*\\.so$|%{_docdir}

maybe python modules should be added to the default value.