It seems that commit 734cf28 breaks the following:

#! /usr/bin/python

import librepo
import time

MIRROR="""https://mirrors.fedoraproject.org/metalink?repo=updates-released-f19&arch=x86_64"""
DESTDIR="./"
URL="""http://linuxdownload.adobe.com/linux/x86_64/"""


if __name__ == "__main__":
    h = librepo.Handle()
    h.destdir = DESTDIR
    h.interruptible = True
    h.repotype = librepo.LR_YUMREPO
    h.url = URL
    h.yumdlist = ["primary", "filelists", "prestodelta", "group_gz"]
    # h.local = True
    h.perform(librepo.Result())
    print(h.url)
    print(h.mirrors)

the error is:
librepo.LibrepoException: (19, 'Yum repo downloading error: Downloading error(s): repodata/filelists.xml.gz - Cannot download, all mirrors were already tried without success; repodata/primary.xml.gz - Cannot download, all mirrors were already tried without success', 'Usable URL not found')

Please treat prior to releasing the new librepo version.