Ideally, we'd build the RC in Rawhide, so we can spot issues and report to upstream. See the python38 package for the new way to mark pre-release versions.
If we decide not to push this into rawhide, we should at least scratch build + CI test it with OpenSSL 1.1.1.
Scratch build completed successfully: https://koji.fedoraproject.org/koji/taskinfo?taskID=32886195 I'll send a PR soon.
https://src.fedoraproject.org/rpms/python2/pull-request/34