When you're choosing packages to install in anaconda, in RHEL4 you could click on the name of the package, i.e. anything in that line I guess. Now in RHEL5 you have to click precisely on the checkbox. Obviously this is only a minor inconvenience, but it does make it a little slower to select packages since you have to be so precise. The thrash of minor behaviors like this gives Linux OSes a less polished feel, to me anyway, but I guess that's what happens if you change widget toolkits or something.
*** This bug has been marked as a duplicate of bug 425809 ***