As of gnome-python2-2.22.1-3.fc10, the Python bindings for libgnome and libgnomeui have moved to a new subpackage named gnome-python2-gnome. Consequently, this package _may_ need to change its gnome-python2 requirement to gnome-python2-gnome. The reason for this change is because libgnome and libgnomeui pull in a large number of dependencies that some of the gnome-python2 subpackages -- such as gnome-python2-gnomevfs -- don't need, but subpackages must still require their parent package. Splitting the libgnome[ui] bindings into a subpackage allows the other subpackages to avoid pulling in lots of unnecessary libgnome[ui] dependencies. See bug #456122 for more details.
I've attached a patch to bug #443754 to upgrade the package from 2.2.10 to 3.0.3 which also includes changes that would resolve this bug.
gramps-3.0.3-0.fc10 has been submitted as an update for Fedora 10. http://admin.fedoraproject.org/updates/gramps-3.0.3-0.fc10
gramps-3.0.3-0.fc10 has been pushed to the Fedora 10 testing repository. If problems still persist, please make note of it in this bug report. If you want to test the update, you can install it with su -c 'yum --enablerepo=updates-testing update gramps'. You can provide feedback for this update here: http://admin.fedoraproject.org/updates/f10/FEDORA-2008-10255
gramps-3.0.3-0.fc10 has been pushed to the Fedora 10 stable repository. If problems still persist, please make note of it in this bug report.